Drusilla was mortal and living in London when Angel first came across her in 1860, as she was confessing her sins (she'd been having premonitions) at Church. Angel slowly drove her mad by killing her family and friends and convincing her that she was the spawn of Satan. She was almost killed in Prague by an angry mob which left her sickly and weak, and Spike, her lover of over a century, brought her to Sunnydale to restore her health. Angel's blood, as her sire, was needed to complete the ritual, but Buffy and the gang arrived in time to stop it before he was killed. Nonetheless, it had been enough time for Drusilla to be restored to health, although the Church they were in collapsed on her and Spike, reversing their roles as he was left in a wheelchair while she was fit and strong. Once she was restored, she had the demon known as The Judge assembled so he might destroy the world, but Buffy stopped them before they could accomplish the plan. When Angel lost his soul and joined forces with Spike, Drusilla and he enjoyed a particularly cruel flirtation in front of the devoted Spike and finally pushed him to join forces with Buffy to stop Angelus so that he might get Dru back. Dru killed Kendra by hypnotizing her and subsequently slitting her throat, and she also used her hypnotic talents on Giles, convincing him that she was Jenny Calendar to get him to reveal the key to wakening the demon Acathla and destroying the world. Spike overpowered Dru during the final battle between Buffy and Angel and she was last seen unconscious in Spike's car driving out of Sunnydale. However, she has left Spike twice since then, once for a Chaos Demon and once for a Fungus Demon, saying that Spike wasn't evil enough for her. She eventually turned up again in LA at the behest of Wolfram and Hart, Angel's rivals, to turn her resurrected grandsire, Darla, back into a vampire. Spurred by nostalgia, she returned to Sunnydale to attempt to patch things up with Spike, only to have Spike reject her in favor of his unrequited love for Buffy.

Juliet Landau, 53, is the daughter of actors Martin Landau and Barbara Bain, and the sister of producer Susan B. Landau (whose movies include Bram Stoker's Dracula, Cool Runnings and An Ideal Husband). She was born in America but spent 4 years in Britain which is where she acquired the British accent she uses for Drusilla. Juliet's career in show business started out in dance - she was a dancer for about 4 and a half years and finally took acting classes which provided her with theatre work and then a supporting role in the movie Ed Wood. Juliet didn't actually audition for the role of Drusilla - Joss had seen her work in Ed Wood and he called her agent; they met and read through some pages of the script and talked over the character, and ultimately she got the part. Subsequent to her work on Buffy, Juliet has worked on a few projects, including Ravager, with Robin Sachs (Ethan Rayne). When she's not acting, Juliet — a self-described workaholic — still attends dance and acting classes and works out avidly. She also enjoys reading and keeping very physical, as well watching Felicity.